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1. Genetic Research and Biobanks Don Chalmers 2. The Need to Down Regulate: A Minimal Ethical Framework for Biobank Research Mats G. Hansson 3. Nordic Biological Specimen Bank Cohorts as Basis for Studies of Cancer Causes and Control: Quality Control Tools for Study Cohorts with More than 2 Million Sample Donors and 100,000 Prospective Cancers Eero Pukkala 4. Biobanks Collected for Routine Healthcare Purposes: Build-Up and Use for Epidemiological Research Joakim Dillner and Kristin Andersson 5. Biobanks and Registers in Epidemiological Research on Cancer Eero Pukkala 6. Study Designs for Biobank-Based Epidemiologic Research on Chronic Diseases Esa L r 7. The EPIC Biobank (European Prospective Investigation into Cancer and Nutrition) Pierre Hainaut, B atrice Vozar, Sabina Rinaldi, Elio Riboli, and Elodie Caboux 8. The AIDS and Cancer Specimen Resource (ACSR) Leona W. Ayers, Sylvia Silver, Jan M. Orenstein, Michael S. McGrath, and Debra L. Garcia 9. Specific Advantages of Twin Registries and Biobanks Jaakko Kaprio 10. The Swedish Multi-Generation Register Anders Ekbom 11. Multigenerational Information: The Example of the Icelandic Genealogy Database Hrafn Tulinius 12. Creation of a New Prospective Research Biobank: The Example of HUNT3 Kristian Hveem 13. Best Practices for Establishing a Biobank G ran Hallmans and Jimmie B. Vaught 14. Extraction, Quantitation, and Functionality Evaluation of DNA from Various Sample Types Malin Ivarsson and Joyce Carlson 15. Cervical Cytology Biobanks as a Resource for Molecular Epidemiology Marc Arbyn, Kristin Andersson, Christine Bergeron, John-Paul Bogers, Magnus von Knebel-Doebertitz, and Joakim Dillner 16. Biobanking of Fresh Frozen Tissue from Clinical Surgical Specimens: Transport Logistics, Sample Selection, and Histological Characterization Johan Botling and Patrick Micke 17. Protein Extraction from Solid Tissue Christer Ericsson and Monica Nist r 18. Collection and Preservation of Frozen Microorganisms Rosamaria Tedeschi and Paolo De Paoli 19. Handling of Solid Brain Tumor Tissue for Protein Analysis Christer Ericsson and Monica Nist r 20. Blood Plasma Handling for Protein Analysis Christer Ericsson and Monica Nist r 21. Biobank Informatics: Connecting Genotypes and Phenotypes Jan-Eric Litton 22. A Practical Guide to Constructing and Using Tissue Microarrays Ian Chandler, Richard Houlston, and Goran Landberg 23. Breast Cancer Genomics Based on Biobanks Asta F rsti and Kari Hemminki 24. Monitoring, Alarm, and Data Visualization Service on Sample Preparing and Sample Storing Devices in Biobanks Halla Hauksd ttir, Krist n J nsd ttir, and Andres Thorarinsson 25. Fresh Frozen Tissue: RNA Extraction and Quality Control Johan Botling and Patrick Micke.